CVE-2025-12921
OpenClinica Community Edition CRF Data Import ImportCRFData xml injection
- Published
- Updated
- Reserved
- Assigned by
- VulDB
Description
A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.
Public exploit
2 references of the record are tagged as an exploit or proof of concept: anyone can try it against an unpatched system. CISA's SSVC rates its exploitation: a proof of concept is public.
Timeline
ID reserved
By VulDB
Published
- 5 days later
· 5 days later
Record updated
Changes after publication (a new score, a public exploit, EPSS crossing 1, 10 or 50 %, leaving KEV) are kept since November 2026; earlier ones are not known.
Scores
| Scored by | CVSS | Score | Vector |
|---|---|---|---|
| VulDBCNA (assigner) | 4.0 | Medium5.3 | CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:N/VA:N/SC:N/SI:N/SA:N/E:P |
| VulDBCNA (assigner) | 3.1 | Medium4.3 | CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:L/I:N/A:N/E:P/RL:X/RC:R |
| VulDBCNA (assigner) | 3.0 | Medium4.3 | CVSS:3.0/AV:N/AC:L/PR:L/UI:N/S:U/C:L/I:N/A:N/E:P/RL:X/RC:R |
| VulDBCNA (assigner) | 2.0 | Medium4.0 | AV:N/AC:L/Au:S/C:P/I:N/A:N/E:POC/RL:ND/RC:UR |
| NVDNVD · Analyzed | 4.0 | Low2.1 | CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:N/VA:N/SC:N/SI:N/SA:N/E:P/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X |
- EPSS (exploitation in 30 days)
- 0.57% · top 52% of all CVEs (8 Nov 2026)
- CISA SSVC
- Exploitation: poc · Automatable: no · Technical impact: partial
The list uses the assigner's score when there is one, then CISA's, then NVD's: Medium 5.3.
Weakness
Affected products
OpenClinica · Community Edition
- affected 3.0
- affected 3.1
- affected 3.2
- affected 3.3
- affected 3.4
- affected 3.5
- affected 3.6
- affected 3.7
- affected 3.8
- affected 3.9
- affected 3.10
- affected 3.11
- affected 3.12
- affected 3.12.0
- affected 3.12.1
- affected 3.12.2
- affected 3.13
References (5)
- VDB-331641 | OpenClinica Community Edition CRF Data Import ImportCRFData xml injection (opens in a new tab)vdb-entrytechnical-description
- VDB-331641 | CTI Indicators (IOB, IOC, TTP, IOA) (opens in a new tab)signaturepermissions-required
- Submit #680872 | OpenClinica OpenClinica Community Edition 3.13, Changeset 74f4df3481b6 (2017-02-28) and 3.12.2, Changeset 347dcfca3d17 (2016-11-21) XML Injection (opens in a new tab)third-party-advisory
- https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md (opens in a new tab)relatedexploit
- https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md#poc (opens in a new tab)exploit
Sources
The same CVE in the primary databases and aggregators, to check against.
- CVE.org record (opens in a new tab)
- CVE List JSON (GitHub) (opens in a new tab)
- NVD (opens in a new tab)
- FIRST EPSS (opens in a new tab)
- OSV.dev (opens in a new tab)
- GitHub Advisories (opens in a new tab)
- CIRCL Vulnerability-Lookup (opens in a new tab)
Badge for a README or a ticket
[](https://cveledger.app/cve/CVE-2025-12921)Record last updated .